Scandium(III) triflate catalyzed 1,4-addition of cyano group to enones using tetraethylammonium cyanide as the cyanide source.
نویسندگان
چکیده
A novel and practical method has been developed for the synthesis of β-cyanoketones using tetraethylammonium cyanide (Et4NCN, TEACN) / Sc(III) triflate and chalcones without the liberation of toxic HCN gas. Availability, safety, easy handling of the reagents, mild conditions of the reaction and high yields, make this method an attractive protocol for the direct synthesis of cyano substituted 1,4-adducts from enones.
منابع مشابه
Scandium(III) trifluoromethanesulfonate catalyzed aromatic nitration with inorganic nitrates and acetic anhydride.
The rare earth metal(III) trifluoromethanesulfonate (rare earth metal(III) triflate, RE(OTf)3) was found to be an efficient catalyst for aromatic nitration with carboxylic anhydride-inorganic nitrate as the nitrating agent. In the presence of a catalytic amount of RE(OTf)3, the nitration of substituted benzenes proceeded to afford the corresponding nitrobenzenes. Especially, scandium(III) trifl...
متن کاملHigh-temperature molecular magnets based on cyanovanadate building blocks: spontaneous magnetization at 230 k.
The molecular-based magnetic materials Cs(2)Mn(||)[V(||)(CN)(6)] (1) and (Et(4)N)(0.5)Mn(l.25)- [V(CN)(5)].2H(2)O (2) (where Et is ethyl) were prepared by the addition of manganese(II) triflate to aqueous solutions of the hexacyanovanadate(II) ion at 0 degrees C. Whereas 1 crystallizes in a face-centered cubic lattice, 2 crystallizes in a noncubic space group. The cesium salt (1) has features c...
متن کاملPeroxynitric Acid: A Convenient Oxygen Source for Oxidation of Organic Compounds Catalyzed by Polyimide-Supported Manganese (III) Tetrakis(4-methoxylphenyl)porphyrin Acetate
In this work, a polyimide (PI) containing triazole units was synthesized using 3,5-diamino-1,2,4-triazole and pyromellitic dianhydride in N-methyl-2-pyrrolidinone. This polymer was used as the support of manganese (III) tetrakis(4-methoxylphenyl)porphyrin acetate to attain a heterogeneous catalyst; namely Mn(T4-OMePP)OAc@PI. The synthesized PI and Mn(T4-OMePP)OAc@PI were characterized by di...
متن کاملTowards a general ruthenium-catalyzed hydrogenation of secondary and tertiary amides to amines
A broad range of secondary and tertiary amides has been hydrogenated to the corresponding amines under mild conditions using an in situ catalyst generated by combining [Ru(acac)3], 1,1,1tris(diphenylphosphinomethyl)ethane (Triphos) and Yb(OTf)3. The presence of the metal triflate allows to mitigate reaction conditions compared to previous reports thus improving yields and selectivities in the d...
متن کاملCyanide metabolism of Pseudomonas pseudoalcaligenes CECT5344: role of siderophores.
Cyanide is one of the most potent and toxic chemicals produced by industry. The jewelry industry of Córdoba (Spain) generates a wastewater (residue) that contains free cyanide, as well as large amounts of cyano-metal complexes. Cyanide is highly toxic to living systems because it forms very stable complexes with transition metals that are essential for protein function. In spite of its extreme ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Acta chimica Slovenica
دوره 60 3 شماره
صفحات -
تاریخ انتشار 2013